Journal of Coronary Artery Disease
Online ISSN : 2434-2173
Volume 29, Issue 3
Displaying 1-6 of 6 articles from this issue
Review Articles
  • Shozo Sueda, Yasushi Fujiwara, Keisho Kurokawa, Tsukasa Kurokawa, Tomo ...
    2023 Volume 29 Issue 3 Pages 49-55
    Published: 2023
    Released on J-STAGE: September 25, 2023
    Advance online publication: August 07, 2023
    JOURNAL OPEN ACCESS
    Statin treatment improves endothelial dysfunction and decreases plaque volume in patients with obstructive coronary artery disease (OCAD) as a pleiotropic mechanism. Clinical outcomes in patients with OCAD under statin therapy are favorable compared with those outcomes for patients without statins. However, the effect of statins may be uncertain in patients with vasospastic angina and nonobstructive coronary artery disease (VSA-NOCAD). Several researchers in South Korea and Japan have reported on the effectiveness of statin therapy in patients with VSA-NOCAD. Flow-mediated dilatation was shown to be improved in VSA patients with statins compared with patients without statins. However, statin treatment was shown to not be effective in reducing the major cardiovascular events (MACEs) in patients with VSA-NOCAD, although after propensity score matching, the prognosis was better in patients with VSA-NOCAD. Furthermore, high-intensity statin therapy showed no clinical utility for mitigating MACEs in patients with VSA-NOCAD.
    Download PDF (565K)
  • The Negative Impacts of Arteriovenous Fistulas and Microvascular Dysfunction
    Hiroyuki Nakajima, Yusuke Watanabe
    2023 Volume 29 Issue 3 Pages 56-61
    Published: 2023
    Released on J-STAGE: September 25, 2023
    JOURNAL OPEN ACCESS
    Coronary artery bypass grafting (CABG) is advantageous for long-term clinical outcomes compared to percutaneous coronary intervention (PCI) in hemodialysis (HD) patients, as PCI has a lower short-term mortality but higher late revascularization risk. Therefore, CABG is very important for HD patients in current clinical practice. In HD patients, the presence of an arteriovenous fistula may lower the flow capacity of the ipsilateral internal thoracic artery (ITA) and induce flow steal, and concomitant microvascular disease (MVD) can cause myocardial ischemia and irreversible myocardial damage even after CABG. The use of the ipsilateral ITA as a free graft or the contralateral ITA as a graft to the left anterior descending artery can be reasonable options. MVD complicates the preoperative evaluation and could worsen clinical outcomes in HD patients. Graft selection and MVD in coronary and systemic circulation are mutually influential future concerns.
    Download PDF (559K)
Original Article
  • Hanae Sasaki, Ryosuke Kowatari, Norihiro Kondo, Masahito Minakawa
    2023 Volume 29 Issue 3 Pages 62-66
    Published: 2023
    Released on J-STAGE: September 25, 2023
    Advance online publication: July 31, 2023
    JOURNAL OPEN ACCESS
    Objective: Placing the internal thoracic artery (ITA) graft ipsilateral to the arteriovenous fistula (AVF) for left anterior descending artery (LAD) revascularization in coronary artery bypass grafting (CABG) in hemodialysis patients may cause coronary steal. However, whether or not ipsilateral or contralateral ITA grafts affect the flow volume and pulsatility index measured based on the transit time flow measurement of the ITA-LAD anastomosis is unclear.
    Materials and methods: Between January 2013 and December 2021, 52 hemodialysis patients who underwent CABG with ITA-LAD anastomosis were divided into two groups based on whether the ITA graft was implemented ipsilateral (n = 42) or contralateral (n = 10) to the AVF.
    Results: The average age at surgery and the duration of hemodialysis were 65.4 ± 8.4 years old and 82.5 ± 54.5 months in the ipsilateral group and 66.9 ± 9.0 years old and 68.8 ± 52.6 months in the contralateral group. There were no significant differences between the ipsilateral and contralateral groups in terms of LAD stenosis (87.4% ± 12.3% vs. 86.8% ± 15.2%), left ventricular ejection fraction (49.0% ± 15.0% vs. 46.7% ± 14.4%), operation time (376.7 ± 83.2 vs. 407.6 ± 117.5 min), intraoperative flow (40.3 ± 24.0 vs 38.5 ± 16.5 mL/min), and pulsatility index (2.7 ± 1.2 vs. 2.3 ± 0.6) for ITA-LAD. There was no graft occlusion on computed tomography in either group at two weeks postoperatively.
    Conclusions: Our study suggests that an ITA graft ipsilateral to the arteriovenous fistula may not always be contraindicated in hemodialysis patients and may be appropriate in most cases.
    Download PDF (872K)
Case Reports
Imaging Case Report
feedback
Top