The present in vitro study was conducted to verify the clinical applicability of a computer-aided design and computer-aided manufacturing (CAD/CAM) inlay restoration. The purpose of the study was to examine the effects of the cavity form, the cement space setting, the resin block type, and the presence of an undercut near the margin on the fit of CAD/CAM inlays fabricated from commercially available hybrid resin blocks. The fit of the CAD/CAM inlay was affected by the cavity form and the cement space values. CAD/CAM inlays with metal inlay cavity forms did not fit as well as modified cavity forms without sharp edges. There was no significant difference in fit among the hybrid resin block products. The results suggest that a cavity that eliminates sharp edges and an undercut, has a rounded open cavity shape, and provides an appropriate cement space is preferable.

Purpose : The purpose of this study is to quantitative assessment of cervical lymph nodes affected by medication-related osteonecrosis of the jaw (MRONJ) using magnetic resonance imaging (MRI).

Materials and Methods : The study group comprised 36 patients (36 women, 58-90 years, mean age 77.67 years) who underwent MRI examination from June 2016 to April 2022. The lymph nodes were measured on the STIR image. A comparison of cervical lymph node number and short-axis size in each group with and without MRONJ was performed using t-test and Mann-Whitney U test. P <0.05 was considered to indicate statistical significance.

Results : The number and size of cervical lymph nodes in the MRONJ group were significantly more and larger, respectively, than those in the non-MRONJ group (P < 0.01).

Conclusion : This study suggests that MRI is useful for quantitative assessment of the cervical lymph nodes affected by MRONJ.