The clinical usefulness of KAMPO (oriental herbal medicine) in the treatment for intractable dental oral diseases (dry mouth, glossodynia, feeding, swallowing disorders, and intractable stomatitis, etc. ) was evaluated in 35 medically compromised patients who sought dental treatment in our department between May 2002 and October 2005. The age of the patients ranged from 34 to 87 years (mean age: 63.9 years), and gender distribution was 5 male patients and 30 female patients. The average concomitant (concurrent) disease (disorder) per patient was 2.8, and the average medication administered to the patient was 4.3. The main reasons for the patient to seek dental attention were unpleasant oral symptom (60.0%), 16 abnormal sensation of the tongue (45.7%), 13 intractable stomatitis (37.1%), 9 dry mouth (25.7%), 8 feeding disorder (22.9%), 6 gingival pain of unknown origin (17.1%), and 4 swallowing disorder (11.4%). Unpleasant oral symptoms were most common (with concurrent existence of concomitant diseases [disorders] ). KANPO for the treatment of each symptom was administered either singly or in combination with several drugs spanning 2 to 8 week. The clinical effect was evaluated with the amount of symptom alleviation and judgment of QOL (as a form of complication in daily activity) by self-evaluation.
The results of the KANPO were 20 cases with complete alleviation of symptoms (57.1%), 14 cases with improvement (40.0%), 1 case that was negligible (2.9%), and there were no cases in which the symptoms deteriorated (0%). The evaluation results of the QOL complications were 20 cases revealed no complications in (57.1%), 9 cases demonstrated small amounts of complications (25.7%), 5 cases with slight complication (14.3%), and 1 case with moderate severity of complication (2.9%), respectively. The overall outcome on the use of KANPO for treatment revealed the KAMPO to be extremely useful in 28 cases (80.0%), considerably useful in 3 cases (8.6%), slightly useful in 3 cases (8.6%), and not useful in 1 case (2.9%), respectively. Moreover, there were no adverse effects recorded during the treatment period.
As for the clinical usefulness of KAMPO in the treatment for intractable dental oral diseases for medically compromised patients as described (mentioned) above with a variety of oral symptoms, it is conclusive that KAMPO demonstrated (revealed) its effectiveness in the treatment of intractable dental oral diseases even if the patients require to take two or more medications concurrently.
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