Background: Cellulitis is an acute bacterial infection of the dermis and subcutaneous
tissue characterized by diffuse inflammation, erythema, swelling, warmth, and tenderness. If the
disease progresses, it can lead to serious complications such as sepsis. In this report, we present
the clinical course of a patient with cerebral palsy and intellectual disability in whom a progressive
odontogenic infection was identified following the onset of lip swelling.
Case presentation: A 53-year-old man presented with a chief complaint lip swelling. Marked lower
lip swelling was observed along with dental caries, accompanied by abscess in the anterior mandibular
region. Blood tests revealed a C-reactive protein (CRP) level of 10.9 mg/dl, and a White blood cell
count of 12,600/μl. The affected teeth were extracted under general anesthesia after antibiotic therapy,
incision, and drainage. The lip swelling resolved, and the patient was diagnosed with lower lip
cellulitis secondary to apical periodontitis.
Conclusion: Lower lip cellulitis is rare. In the present case, the patient with intellectual disability was
unable to express subjective symptoms; however, lip swelling was noticed by a caregiver, which led
to the patient visiting our department. Although the extension of inflammation to the oral floor could
have resulted in more severe symptoms, the spread to the lip allowed for early recognition and timely
intervention. This case highlights the importance of close observation by caregivers and clinicians,
especially in patients with communication difficulties, for early detection of potentially serious
infections.
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