We measured thromboelastometry (ROTEM
TM, A10: value of 10 minutes), fibrinogen concentration, and platelet counts during cardiopulmonary bypass. We estimated the necessity for blood transfusions from the end of cardiopulmonary bypass to 24 hours post-surgery in 51 patients undergoing adult cardiac surgery.
The values that indicated the necessity for fresh frozen plasma were FIBTEM (A10) <6 mm and fibrinogen concentration<145 mg/dl. The values that indicated the necessity for platelet concentrates were platelet counts <80,000/μl and [EXTEM (A10)-FIBTEM (A10)] <30 mm.
The results of this study indicate that, 1) FIBTEM (A10) estimates the necessity for fresh frozen plasma as well as fibrinogen concentration, 2) [EXTEM (A10)-FIBTEM (A10)] and platelet counts estimates the necessity for platelet concentrate, and 3) normalization of fibrinogen concentration >200 mg/dl or FIBTEM (A10) >10 mm and normalization of platelet counts >80,000/μl or [EXTEM (A10)-FIBTEM (A10)] >30 mm decreases the amount of post-operative bleeding by 30~50%.
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