The purpose of this study was to investigate the interaction between sleep duration and age for metabolic syndrome risk factors (MetSR) in Japanese women. Sleep duration and sedentary behavior time were measured by self-reported questionnaire and tri axial accelerometer. MetSR was assessed by blood samples, blood pressure (BP) and body composition. In young and middle-aged women were divided into 4 groups: high sleep time (ST-Long), low sleep time (ST-Short), high sedentary behavior time, low sedentary behavior time groups based on the mean value of sleep time and sedentary behavior time in each age group. Significant correlation was observed between sleep duration and sedentary behavior time both young and middle-aged women, and there was no significant interaction between sedentary behavior time and age on any MetSR by two-way ANOVA. However significant interaction was seen between sleep time and age on body fat percentage and arteriosclerotic index. Body fat percentage in ST-Long was significantly lower than that in middle aged compared with in young subjects, but not in ST-Short. Additionally, arteriosclerotic index in ST-Long was also significantly lower than that in middle aged compared with in young subjects, but not in ST-Short. These results suggest that it is need to consider the age effect to investigate the relationship between sleep time and MetSR.

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