Annual Meeting of the Japanese Society of Toxicology

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The 37th Annual Meeting of the Japanese Society of Toxicology

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A single dose vascular irritability study of benzodiazepine sedative-hypnotic intravenous injections in rabbits

Osamu MITANI, Yukihiko WATANABE, Yoshiro YAMAMURA, Koji TAYA, Manabu S ...

Session ID: P19
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.219.0

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Investigation of usability in vascular irritation study by infusion method in rabbit

Akinori KIYA, Ryoko SEKIMOTO, Hiroyuki ARITOMI, Toshiyuki MARUYAMA, No ...

Session ID: P20
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.220.0

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Establishment of stability acquired technology of electrocardiogram by Macaca fascicularis that use jacket type telemetry system

Tatsuya ITO, Yukihito MIURA, Tomihiko KOIZUMI, Yuichiro YAMADA, Ryuich ...

Session ID: P21
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.221.0

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A study of phototoxicity following intravenous administration to BALB/c mice

Shinji UTSUNOMIYA, Yoshihiro TAKAHASHI, Yusuke YAMASHITA, Yasuharu OTS ...

Session ID: P22
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.222.0

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The holter ECG in cynomolgus monkeys -Evaluation on the JET system-

Sou WADA, Tunehiro TANIGAWA, Hidekashu HOSODA, Takaya ITOU, Kennosuke ...

Session ID: P23
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.223.0

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Relation between drug-induced hepatic damage and oxidative stress in accelerated senescence model mice (SAMP8): Exhaustive analyses of gene expression using microarray

Hiro FUJISAWA, Makoto KONNO, Tomohiro YAMAMOTO, Morie NISHIWAKI, noriy ...

Session ID: P24
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.224.0

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Effect of donepezil hydrochloride on object recognition in rats

Hiroyuki ABE, Takumi OKAJIMA, Hirotada TSUTSUMI, Naoko KATSU, Michio T ...

Session ID: P25
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.225.0

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Activity of MNU from different makers

Kazuhiko MACHIDA, Koji URANO, Masumi YOSHIMURA, Masashi TOMISAWA, Masa ...

Session ID: P26
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.226.0

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Lot-to-lot difference of gene expression change in the liver of chimeric mice treated with various hepatotoxicants

Shin-ichiro NAGATSUKA, Darina HYNES, Shin-ichi NINOMIYA, Masakazu KAKU ...

Session ID: P27
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.227.0

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Basic approach of in vitro sensitization test using the changes of cell surface thiols (SH test)

Morihiko HIROTA, Akira MOTOYAMA, Shigenobu HAGINO, Hirokazu KOUZUKI, H ...

Session ID: P28
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.228.0

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Evaluation of eye irritation using a reconstructed cornea model

Masakazu KATOH, Takahiro OGASAWARA, Akemi USUI, Fumiyasu HAMAJIMA, Tom ...

Session ID: P29
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.229.0

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The zebrafish (Danio rerio) as a model organism for toxicity screening

Yuki INOUE, Katsumi MORISHITA

Session ID: P30
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.230.0

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Development of a fluorescent-based in vitro assay for drug-induced lipid accumulation

Akemi MATSUMOTO, Saku MIYAMOTO, Megumi HIRAYAMA, Chihiro KUROZUMI, Iku ...

Session ID: P31
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.231.0

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Structure-activity relationship model for prediction of skin sensitization using novel descriptor calculated by quantum chemical calculation

Hirohisa NAGAHORI, Kaoru YOSHIOKA, Takashi MORIMOTO, Mika OTA, Shozi S ...

Session ID: P32
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.232.0

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Development of in vitro alternative method for developmental toxicity using mouse embryonic stem cells

Noriyuki SUZUKI, Nobuyuki HORIE, Satoshi ANDO, Koichi SAITO

Session ID: P33
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.233.0

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Analysis of marker genes for prediction of embryotoxicity in neural differentiation using mouse embryonic stem cells

Noriyuki SUZUKI, Satoshi ANDO, Nobuyuki HORIE, Koichi SAITO

Session ID: P34
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.234.0

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Local lymph node assay (LLNA) using CBA mice - Comparison of RI and BrdU methods

Yasuharu OTSUBO, Yoshihiro TAKAHASHI, Takahiro YOSHIKAWA, Yusuke YAMAS ...

Session ID: P35
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.235.0

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Effects of minoxizil on cultured rat embryos

atsushi YOKOYAMA, masaharu AKITA

Session ID: P36
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.236.0

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Development of alternative to oral mucous membrane irritation test by modified STE test

Yoshihiro YAMAGUCHI, Maki NAKAMURA, Lina BIAN, Xiaolin LI, Lu QIU

Session ID: P37
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.237.0

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The development of an ultra-short-term lung carcinogenicity study using rasH2 mice

Mayumi KAWABE, Takamasa NUMANO, Mayuko SUGURO, Yuko DOI, Norio IMAI, F ...

Session ID: P38
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.238.0

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Use of toxicogenomic profiling in single-dose studies for predicting the type of liver weight increase

Kaori ABE-TOMIZAWA, Yohsuke MINOWA, Katsumi MORISHITA, Hiroshi YAMADA, ...

Session ID: P39
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.239.0

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Computational approach for assessment of glutathione depletion based on gene expression data

Yoshinobu IGARASHI, Naoki KIYOSAWA, keiichi MINAMI, Masayuki KANKI, Se ...

Session ID: P40
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.240.0

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Toxicogenomics approach for identifying biomarker of plasma ALT elevation without hepatic necrosis

Takashi TANAHARU, Manabu OKUYAMA, Yoshiaki TAGAWA, Yukiharu MATSUMOTO, ...

Session ID: P41
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.241.0

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A study about the local existence of the expression change of the renal tubule disorder marker gene in the rat kidney

Seiko UEDA, Takeki UEHARA, Yousuke MINOWA, Noriyuki NAKATU, Hiroshi YA ...

Session ID: P42
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.242.0

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Gene set-level network anaysis using a toxicogenomics database

Naoki KIYOSAWA, Noriyo NIINO, Kyoko WATANABE, Sunao MANABE, Atsushi SA ...

Session ID: P43
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.243.0

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Exploration of genomic and metabonomic biomarkers for rat skeletal muscle injury

Hisakuni OBAYASHI, Shusuke YAMAUCHI, Wataru SAITOH, Makoto SHIRAI, Nor ...

Session ID: P44
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.244.0

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Construction of a toxicogenomic prediction model for the hepatocyte necrosis in rats

Ko OMURA, Takashi MATSUDA, Daisuke KIGAMI, Kotaro TAMURA, Masayuki KAN ...

Session ID: P45
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.245.0

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The effects of DMSO on gene expression in human hepatocytes

Kayo SUMIDA, Yoshinobu IGARASHI, Naoki TORITSUKA, Tomochika MATSUSHITA ...

Session ID: P46
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.246.0

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Investigation of marker genes for drug-induced bile duct proliferation using toxicogenomics database

Tomochika MATSUSHITA, Hironori MUTOH, Motooki ASHIHARA, Masayuki MISHI ...

Session ID: P47
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.247.0

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Metabonomic investigation of hepatotoxicity biomarker using acetaminophen and the analog

Wataru SAITO, Naoki KIYOSAWA, Shusuke YAMAUCHI, Kazuyoshi KUMAGAI, Tak ...

Session ID: P48
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.248.0

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Toxicogenomic approach for identifying marker genes of liver toxicity in rat whole blood

Noriyuki NAKATSU, Masayuki KANKI, Hiroshi YAMADA, Tetsuro URUSHIDANI, ...

Session ID: P49
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.249.0

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Estimation of genomic markers for chemically induced liver fibrosis in rats

Chiaki HANDA, Shinichi MUTO, Noriyuki NAKATSU, Satoshi AKAHANE, Hirosh ...

Session ID: P50
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.250.0

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The study of biomarkers for the generation of reactive metabolites

Toshihiro KAI, Takahiro YUDATE, Mikio AOKI, Toru YAMADA, Toru KIMURA, ...

Session ID: P51
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.251.0

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Expression profiling of endoplasmic reticulum stress related genes in rat liver using TGP large-scale database

Naoki TORITSUKA, Noriyuki NAKATSU, Atsushi ONO, Hiroshi YAMADA, Tetsur ...

Session ID: P52
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.252.0

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Investigation of mechanism and biomarkers on testicular toxicity of the rat treated with ethylene glycol monomethyl ether (EGME) by metabonomic analysis

Yosuke ANDO, Makoto TAKEI, Wataru SAITOH, Tomoe TANIMOTO, Naoki KIYOSA ...

Session ID: P53
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.253.0

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Inhibitory effects of xanthoangelol and 4-hydroxyderricin, from Angelica keiskei, on growth in human gastric cancer cells

Arisa TAKEUCHI, Minoru Sakaguchi, Kimiye BABA, Masahiko TANIGUCHI, Mak ...

Session ID: P54
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.254.0

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Relation between ethanol-induced oxidative stress and Fas death receptor mediated apoptosis in human hepatoma (SK-Hep-1) cells

Yoshiya MOCHIZUKI, Mayumi TSUJI, Hideto OYAMADA, Michi OTA, Katsuji OG ...

Session ID: P55
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.255.0

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Contribution of mitochondrial membrane-bound glutathione transferase to copper ioninduced mitochondrial permeability transition

Enkhbaatar ULZIIKHISHIG, Naoki IMAIZUMI, Yoko ANIYA

Session ID: P56
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.256.0

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Involvement of advanced glycation end-products, pentosidine and N-(carboxymethyl) lysine, in doxorubicin-induced cardiomyopathy in rats

Tomoyuki MORIYAMA, Masayuki KEMI, Toshiharu HORIE

Session ID: P57
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.257.0

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Effect of oxidative derivatives of sebum on human skin cells

Tadashi UCHINO, Kiyotaka NAKAGAWA, Yosiaki IKARASHI, Testuji NISHIMURA ...

Session ID: P58
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.258.0

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Gene expression profile in rat ovarian follicle during ovulation

Kenjiro TSUBOTA, Masayuki KANKI, Ayano TAKEUCHI, Takahisa NOTO, Katsuh ...

Session ID: P59
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.259.0

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Influence of diluent on the pharmacodynamics and pharmacokinetics of somnopentyl in mouse

Naoyuki ASAKAWA, Jun OTSUKA, Shoichi KADO, Tatsumi MIZUTANI, Kazuhiko ...

Session ID: P60
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.260.0

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Genistein inhibits skeletal development in zebrafish embryo

Hironobu KATSUYAMA, Masahiro MATSUSHIMA, Hajime HINENOYA, Shigeko FUSH ...

Session ID: P61
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.261.0

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Determination of Aluminium in rat serum

Fumiko ISHIKAWA, Mariko HIRATA, Masao SUNAGA, Takuo NAKAYAMA, Masao KI ...

Session ID: P62
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.262.0

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A new kinetic analysis of double-strand break on large DNA molecules based on singlemolecule observation

Tatsuya TAKATA, Hirofumi KURITA, Hachiro YASUDA, Kazunori TAKASHIMA, A ...

Session ID: P63
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.263.0

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Evaluation of measurement and differentiation of nucleated cell in bone marrow using XT-2000iV

Takashi SAKATA, Ayako NISHIO, Yasunori ODA, Norihisa SHIOHARA, Kiyoshi ...

Session ID: P64
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.264.0

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The effects of nasal instillation of nanoparticle-rich diesel exhaust particle (NRDEP) on the central nervous system in rats

Syunji YOKOTA, Hiromasa TAKASHIMA, Takashi MIYAHARA, Yuka YOSHIDA, Tsu ...

Session ID: P65
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.265.0

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Distribution analysis of amorphous nanosilica to the testis for the safety scientific assessment

Yuki MORISHITA, Yasuo YOSHIOKA, Kohei YAMASHITA, Kazuma HIGASHISAKA, T ...

Session ID: P66
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.266.0

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Influence of surface properties of amorphous nano-silica particles on in vivo biological behavior

Saeko TOCHIGI, Tomoaki YOSHIKAWA, Hiromi NABESHI, Yasutarou NAKAZATO, ...

Session ID: P67
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.267.0

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Pulmonary responses to multi-wall carbon nanotubes after single intratracheal instillation in rats

Masato NAYA, Norihiro KOBAYASHI, Shigehisa ENDOH, Junko MARU, Makoto E ...

Session ID: P68
Published: 2010
Released on J-STAGE: August 18, 2010

DOIhttps://doi.org/10.14869/toxp.37.0.268.0

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