The Cl
--activity in the endolymph of the endolymphatic sac and in the cochlear duct were measured with Cl
--sensitive double barrelled microelectrodes. The Cl
--activity in the endolymphatic sac fluid was lower than in the cochlear duct. A small positive DC-potential was recorded in the endolymphatic sac. During anoxia DC-potential decreased and the Cl
--activity in the endolymphatic sac increased. The K/Na ratio in the epithelial cells and subepithelial tissue of endolymphatic sac was measured by LAMMA
® technique. The K/Na ratio in the epithelial cells decreased after ethacrynic acid injection (60 mg/kg i. v.). These findings suggest that the ions in the endolymphatic sac are actively transported inwards and outwards.
抄録全体を表示