A plethysmographic system has been described to provide ventilatory functional parameters of anesthetized, tracheotomized rats. They include respiratory mechanics, lung volume, static pressure-volume curve for lung, and flow-volume curve. The dynamic response of the apparatus and basic problems involved in the present techniques were examined. The measurements performed in two groups of Wistar male rats yielded the results exactly predictable from differences in body weights and lung volumes. These results are compared with those published by other investigators for Fisher female rats.
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