Two New Steroidal Derivatives from the Fruit Body of Chlorophyllum molybdites

Kazuko YOSHIKAWA; Mizuho IKUTA; Shigenobu ARIHARA; Eiko MATSUMURA; Satoshi KATAYAMA

doi:10.1248/cpb.49.1030

Notes

Two New Steroidal Derivatives from the Fruit Body of Chlorophyllum molybdites

Kazuko YOSHIKAWA, Mizuho IKUTA, Shigenobu ARIHARA, Eiko MATSUMURA, Satoshi KATAYAMA

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Keywords: Chlorophyllum molybdites, Agaricaceae, uerido ergostene, Kato III cell

JOURNAL FREE ACCESS

2001 Volume 49 Issue 8 Pages 1030-1032

DOI https://doi.org/10.1248/cpb.49.1030

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Abstract

Two new steroid derivatives, (22E, 24R)-3α-ureido-ergosta-4, 6, 8(14), 22-tetraene (1) and (22E, 24R)-5α, 8α-epidioxyergosta-6, 9, 22-triene-3β-ol 3-O-β-D-glucopyranoside (2) were isolated from the fruit bodies of Chlorophyllum molybdites (Agaricaceae). The structures were established by spectroscopic and chemical methods. These compounds exhibited cytotoxicity against Kato III cells.

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