Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
An Efficient Synthesis of 1, 1-Disubstituted Hydrazines
YASUOKI MURAKAMIYUUSAKU YOKOYAMACHIYOKO SASAKURAMAKIKO TAMAGAWA
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1983 Volume 31 Issue 2 Pages 423-428

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Abstract
1, 1-Disubstituted hydrazines were prepared from the corresponding 1, 1-disubstituted ureas by means of the Hofmann rearrangement reaction. The yields were fairly good, except from the ureas susceptible to oxidation, and thus the present method represents an additional and efficient procedure for the synthesis of 1, 1-disubstituted hydrazines.
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© The Pharmaceutical Society of Japan
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