Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
NOTE
Changes in the Plasma Testosterone Level and Testicular Superoxide Dismutase Activity of 5 Azoospermic Beagles after GnRH Analogue Injections
Eiichi KAWAKAMIDaiki KURODATatsuya HORIToshihiko TSUTSUI
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Keywords: azoospermia, canine, SOD
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2007 Volume 69 Issue 5 Pages 561-562

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Abstract

The peripheral blood plasma testosterone (T) levels and superoxide dismutase (SOD) activity were measured in 5 azoospermic (AZ-) beagles. The mean values in the AZ-dogs were significantly lower than in 7 control beagles (P<0.001). Subcutaneous injections of 1 μg/kg GnRH analogue three times weekly in the AZ-dogs induced significant increases in mean T level and SOD activity (P<0.05) and improvement in spermatogenesis. Thus, spermatogenic function in the dog appears to be maintained by T and normal SOD activity in the testis.

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© 2007 by the Japanese Society of Veterinary Science

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https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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