An Organic Field-effect Transistor with an Extended-gate Electrode Capable of Detecting Human Immunoglobulin A

Tsukuru MINAMIKI; Tsuyoshi MINAMI; Yui SASAKI; Ryoji KURITA; Osamu NIWA; Shin-ichi WAKIDA; Shizuo TOKITO

doi:10.2116/analsci.31.725

Notes

An Organic Field-effect Transistor with an Extended-gate Electrode Capable of Detecting Human Immunoglobulin A

Tsukuru MINAMIKI, Tsuyoshi MINAMI, Yui SASAKI, Ryoji KURITA, Osamu NIWA, Shin-ichi WAKIDA, Shizuo TOKITO

Author information

Tsukuru MINAMIKI
Research Center for Organic Electronics (ROEL), Graduate School of Science and Engineering, Yamagata University
Tsuyoshi MINAMI
Research Center for Organic Electronics (ROEL), Graduate School of Science and Engineering, Yamagata University
Yui SASAKI
Research Center for Organic Electronics (ROEL), Graduate School of Science and Engineering, Yamagata University
Ryoji KURITA
Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)
Osamu NIWA
Research Center for Organic Electronics (ROEL), Graduate School of Science and Engineering, Yamagata University
Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)
Shin-ichi WAKIDA
Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)
Shizuo TOKITO
Research Center for Organic Electronics (ROEL), Graduate School of Science and Engineering, Yamagata University

Keywords: Organic field-effect transistor, immunosensor, label-free, immunoglobulin A, self-assembled monolayer

JOURNAL FREE ACCESS
Supplementary material

2015 Volume 31 Issue 7 Pages 725-728

DOI https://doi.org/10.2116/analsci.31.725

Details

Abstract

We herein report on the development of an extended-gate type organic field-effect transistor (OFET)-based immunosensor for the detection of human immunoglobulin A (IgA). The titration results of IgA exhibited shifts in the transfer characteristics of the OFET sensor device with increasing IgA concentration. A linear detection range from 0 to 10 μg/mL was realized with a detection limit of 2.1 μg/mL, indicating that the OFET-based immunosensor can be potentially applied to the monitoring of infectious diseases and psychological stress in daily life.

Fullsize Image

Corresponding author

Register with J-STAGE for free!