Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Notes
Araloside A, an Antiulcer Constituent from the Root Bark of Aralia elata
Eun Bang LeeOon Ja KimSam Sik KangChoonsik Jeong
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2005 Volume 28 Issue 3 Pages 523-526

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Abstract

Araloside A, a potent inhibitor of gastric lesion and ulcer formation in rats, was isolated from the root bark of Aralia elata through a bioassay-guided separation procedure. The compound exhibited significant reduction of HCl·ethanol-induced gastric lesions and aspirin-induced gastric ulcers at oral doses of 50 and 100 mg/kg, respectively. These activities are comparable to those of cimetidine.

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© 2005 The Pharmaceutical Society of Japan
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