Adult-onset Invasive Haemophilus influenzae Type f Caused by Acute Lower Leg Cellulitis

Yuko Usui; Risako Kakuta; Makoto Araki; Taigo Sato; Yoshiaki Gu; Hisakazu Yano; Norihide Taniuchi

doi:10.2169/internalmedicine.55.6080

CASE REPORTS

Adult-onset Invasive Haemophilus influenzae Type f Caused by Acute Lower Leg Cellulitis

Yuko Usui, Risako Kakuta, Makoto Araki, Taigo Sato, Yoshiaki Gu, Hisakazu Yano, Norihide Taniuchi

Author information

Keywords: H. influenzae type b, H. influenzae type f, multilocus sequence typing, cellulitis, invasive

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 13 Pages 1811-1813

DOI https://doi.org/10.2169/internalmedicine.55.6080

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Abstract

In Japan, routine Haemophilus influenzae type b (Hib) vaccination began in 2013. Thus, similar to other countries, a strain shift is expected in the near future. We experienced a case of H. influenzae type f (Hif) bacteremia in a 66-year-old man. The primary focus of the infection was the soft tissue of the left lower leg, which is an extremely rare origin in adults. Subsequently, we conducted multilocus sequence typing and identified the strain as sequence type 124, which is the most common invasive strain of Hif worldwide. This case may mark the beginning of an Hif strain shift in Japan.

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