Primary Embryonal Carcinoma of the Retroperitoneum

Nobuyuki OHKUBO; Tohru OGIHARA; Toshihiro MIURA; Kenzo SOEJIMA; Shigeru IYORI; Yoshikiyo AKASAKA; Masao TASHIRO

doi:10.2169/internalmedicine.32.295

Nobuyuki OHKUBO, Tohru OGIHARA, Toshihiro MIURA, Kenzo SOEJIMA, Shigeru IYORI, Yoshikiyo AKASAKA, Masao TASHIRO

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Keywords: extragonadal, germ cell tumor, PVB therapy, cisplatin, alpha-fetoprotein, human chorionic gonadotropin

JOURNAL FREE ACCESS

1993 Volume 32 Issue 4 Pages 295-297

DOI https://doi.org/10.2169/internalmedicine.32.295

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Abstract

A 32-year-old man with primary embryonal carcinoma of the retro peritoneum, a very rare condition, is reported. The disease took an acute course with rapid enlargement of cervical and inguinal lymph nodes, and high serum alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) values were observed. His testes were, however, intact. Remarkable tumor regression was achieved by systemic combination chemotherapy with cisplatin, vin lastine, and bleomycin (PVB therapy). This chemotherapy is beneficial even in advanced cases. In the two years since therapy, no recurrence has been observed.
(Internal Medicine 32: 295-297, 1993)

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