The purpose of this study was to discuss the effectiveness of anatomical exercise by using a type of dog food called “Boiled Chicken Head” in a lower secondary school science class and to analyze the experimental data results with regard to male and female students. In the unit “Body structure and functions of animals” of 2^nd grade lower secondary school science class, the following 4 points were clarified after the anatomical exercise and the discussion about its effectiveness. 1. Both male and female students were able to recognize each of the parts of the brain at an acceptable level. 2. After the anatomical exercise, the minds of both male and female students were changed to become more positive toward anatomical exercises. 3. During the anatomical exercise, both male and female students maintained their interest highly. 4. The anatomical exercise did not have any negative influences on the male or female students’ attitudes toward science topics, such as “being interested in nerve system and function” and “respect for life”.