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Annals of Business Administrative Science
Vol. 15 (2016) No. 3 p. 129-138

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http://doi.org/10.7880/abas.0160224a


In pharmaceutical research and development of drugs, discovering new drugs from a large number of potential alternatives (chemical compounds), which are theoretically as many as 1060, is an important challenge. Here the new-drug discovery process was explored through a case study on Rozerem from Takeda Pharmaceutical Company Limited. Although the recent mainstream approach is to generate and test a large number of alternatives using automation technologies, Rozerem was discovered through exploration of a small number of alternatives with rational chemical compound design, based on researchers’ experience and knowledge.

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