Annals of Business Administrative Science
Online ISSN : 1347-4456
Print ISSN : 1347-4464
Drug Discovery Process
A Case Study on Takeda
Kenichi KUWASHIMA
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Volume 15 (2016) Issue 3 Pages 129-138

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Abstract

In pharmaceutical research and development of drugs, discovering new drugs from a large number of potential alternatives (chemical compounds), which are theoretically as many as 1060, is an important challenge. Here the new-drug discovery process was explored through a case study on Rozerem from Takeda Pharmaceutical Company Limited. Although the recent mainstream approach is to generate and test a large number of alternatives using automation technologies, Rozerem was discovered through exploration of a small number of alternatives with rational chemical compound design, based on researchers’ experience and knowledge.

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ABAS is supported by Grant-in-Aid for Publication of Scientific Research Results from the Japan Society for the Promotion of Science.

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