抄録
Brain tumors have the highest incidence of childhood solid can cers and they also
have the highest mortality rate among childhood cancers. One fa ctor cited for
improved prognosis in cancer is improvement in surgical extraction rate, but types
of childhood brain tumors are more diverse in comparison to tho se of adults, and it
is at present exceedingly difficult for even an experienced pathologist to perform an
accurate diagnosis. We have developed a technique for freezing under magnetic field
for the purpose of internal organ cryopreservation, and we cond ucted this study after
considering that this freezing technique could be useful for ra pid diagnosis utilizing
frozen tissue during surgery. Results showed the arrangement of neurons to be in much
better order with brain tissue frozen under magnetic field than that which was frozen
by liquid nitrogen. For pancreatic tissue, it was found that in sulin staining was clearer
for freezing performed under magnetic field than with liquid nitrogen. In short, we found
that this technique is not simply for the preservation of tissu e, but has the potential to
improve the accuracy of pathological diagnosis and surgical ext raction rate as well
as limiting chemotherapy and radiation therapy. This is the principal outcome that will
contribute to an improved quality of life (QOL) for childhood cancer patients.
