Neuroendocrine-Immune Interactions and Starvation in Mucosal Immunity and Mucosal Inflammation

Abstract

Mutual communication among the immune, neuroendocrine and metabolic systems is essential for the maintenance of gastrointestinal mucosal function. A unique barrier system by the mucosal immune system handles a myriad of infectious and food antigens, while the neuroendocrine system interplays with the immune system in the intestinal mucosa. The close relation between these two systems is associated with the pronounced effects of stress and metabolic changes.