ACTA HISTOCHEMICA ET CYTOCHEMICA
Online ISSN : 1347-5800
Print ISSN : 0044-5991
ISSN-L : 0044-5991
REGULAR ARTICLES
Maturation of Three Kinds of Keratin Networks in the Absorptive Cells of Rabbit Duodenum
Hirohiko IwatsukiMasumi Suda
Author information
JOURNAL FREE ACCESS

2005 Volume 38 Issue 3 Pages 237-245

Details
Abstract
Keratins (Ks) expressed in the absorptive cells of rabbit duodenal epithelium were studied immunohistochemically and immunoelectron microscopically. These keratins were classified into three groups based on their distribution: keratins forming an apex network just under the terminal web, those forming a Golgi-associated network surrounding the Golgi apparatus, and those forming an entire cytoplasmic network. The apex network was composed of K5/K18 keratin filaments. The Golgi-associated network at first consisted of K8/K14 keratin filaments alone. When the cell migrated out of the crypt to the mid-villus, actin and K7/K17 keratin filaments successively entered this network. The entire cytoplasmic network was detected at the villus base, and consisted of K7/K17 keratin filaments. Thereafter, K5/K18 keratin filaments entered this network during migration of the cell. The apex network may serve to maintain cell-cell contact, since its filaments are tightly anchored to desmosomes. The Golgi-associated network may be involved in the maintenance of the complex structure of the Golgi apparatus, since its filaments constitute a three-dimensional network around the organelle. The entire cytoplasmic network may play a major role in the maintenance of cell structure and the distribution of cell organelles.
Content from these authors
© 2005 By the Japan Society of Histochemistry and Cytochemistry
Previous article
feedback
Top