HUMAN CHORIONIC GONADOTROPIN (HCG) STIMULANT TO IMMUNOGLOBULIN FORMATION IN HUMAN EMBRYONIC LYMPHOID APPARATUS BY FLUORESCENT ANTIBODY TECHNIQUE

Abstract

Remarkable increase of quantity of HCG in earlier stage of normal pregnancy has been requested in further investigation on its biological and immunological properties. Normal human embryo presented the production of immunoglobulins in the medullar thymus which was the initial responsive organ among the lymphoid apparatus of human embryo in the 12th week of gestation. The so-called blood thymic barrier was apt to be broken by continuous strong stimulation of HCG to promote the histological and functional development of the medullar thymus in production of human embryonic immunoglobulins.
The detection was done by fluorescent antibody technique on normal human embryos which were obtained at legitimate induced abortion or at spontaneous abortion due to mainly incompetent cervix.