THE DISTRIBUTION OF TAMM-HORSFALL GLYCOPROTEIN IN URINARY SYSTEM OTHER THAN KIDNEY AND IN PROSTATE GLAND

Abstract

Immunofluorescent studies using antibodies against Tamm-Horsfall urinary glycoprotein were performed in order to study the localization of glycoprotein in the human, rat and dog urinary system other than kidney and in the prostate gland. All extracts from ureter, urinary bladder, urethra and prostate gland showed a single distinct zone of precipitation with the rabbit anti-Tamm-Horsfall glycoprotein antibody in the Ouchterlony double diffusion test. Tamm-Horsfall glycoprotein was observed in both the mucous membrane and the muscular layer of the urinary system other than the kidney, and also in the prostate gland.