Abstract
Localization of amylase and lysozyme within the serous secretory granule of the human parotid and submaxillary glandular acinocytes was studied with immuno-electron microscopy, using the protein A-gold technique. Antigenic sites of amylase were observed to be localized diffusely throughout the secretory granule and those of lysozyme in its central core of the granule. Therefore, it was concluded that amylase disperses within and throughout the granule, and lysozyme tends to concentrate in the central core.