Abstract
Cyclic nucleotide phosphodiesterase was demonstrated in the hippocampus of the hamster by an immunohistochemical method. The enzyme was localized in the somata of pyramidal and granular cells and their dendrites. Furthermore, capillaries and the neuropil were strongly stained. Glial cells could be detected in fibre layers (corpus callosum). The antiserum was produced against bovine heart Ca2+/calmodulin phosphodiesterase and cross-reacted with brain phophodiesterase.
