IMMUNOHISTOCHEMICAL LOCALIZATION OF ANP IN THE PULMONARY VEINS OF THE RAT

Abstract

The presence of atrial natriuretic peptide (ANP) in the striated myocytes of pulmonary veins in rat was studied by immunohistochemical methods. In general, the immunoreactivity of the pulmonary myocardium was less intense than found in the left atrium. In the inner circular layer of the pulmonary myocardium, some striated myocytes were moderately granular stained. The staining was mainly localized to the paranuclear areas, while some granules were also distributed throughout the sarcoplasm.