Abstract
α-actinin is an actin-binding protein, closely associated with actin-containing stress fibers and, in particular, with their membrane-bound terminals. Using the immunohistochemical pre-embedding PAP method, we have demonstrated the presence of actin-binding protein in the cerebellar cortex of adult rats at both light and electron microscopic levels. α-actinin immunoreactivity has been demonstrated within Bergmann glial cells, Golgi and stellate cells, astrocytes and cerebellar capillaries. These results suggest the essential involvement of this actin-binding protein in the cerebellar cortex function.