A new model has been proposed for evaluating the discharge coefficient and flow angle at an inflow opening for cross-ventilation based on the previous analysis of the flow structure by the Large Eddy Simulation. This model is based on the idea that the cross-ventilation flow structure in the vicinity of an inflow opening creates dynamic similarity under the condition that the ratio of cross-ventilation driving pressure to dynamic pressure of cross flow at the opening is consistent. Wind tunnel model study was carried out to reproduce cross-ventilation by attaching suction fan at the leeward side of the building model. Discharge coefficients at stagnant surrounding condition with suction flow correspond well with those exposed to external wind with extremely large suction flow. Total pressure at the opening is preserved even when flow is separated at the upstream corner. It was confirmed that the proposed model can be applied to almost any directions and opening positions.