Recently attention has been focused on countermeasures against microorganisms such as viruses and microbe, in connection with pandemics of new forms of influenza or SARS, and the occurrence of bioterrorism. Also, in pharmaceutical or food production facilities, a high standard of internal environment of the facility is required, including countermeasures against microorganisms. These countermeasures from the facility point of view include partitioning of work zones (zoning), and cleaning the air using HEPA filters. However, when workers/researchers are working within a facility, dispersion of dust or adhering microbe brought in from clothes, etc., cause pollution of the air. In this report, the sterilization performance of weak acid hypochlorous solution used as the chemical substance was verified. In addition, the sterilization performance in an actual space varied not only with the chemical substance used, but also with the condition of the room, the air conditioning system, the method of spraying, etc. Therefore, from the above sterilization performance tests using chemical substances, the raw data required for a computational fluid mechanics (CFD) model were derived. A method that enables the effect of the chemical substance to be predicted under various conditions was investigated, and the results are reported.
