This research aims to quantify the relationship between airborne algal growth/death on the exterior walls of the building and environmental factors such as surface temperature and humidity. Based on this, the study proposes a prediction model for the algal growth, where the algal growth was evaluated as algal cell number. The proposed model was used to simulate the change in algal cell number (growth and/or death), taking into consideration the temperature, humidity, and incident solar radiation. Results indicate that the algal growth rate agreed well with the measured L* value (brightness).