This paper proposed a method to estimate the structural performance (stiffness, capacity, failure mode and ductility) of the Reinforced Concrete (RC) frame with cast-in-place non-structural'RC walls (spandrels, sidewalls and mullions): The shear-loading tests for onestory one-span RC frame with non-structural walls were conducted to investigate the influence of non-structural walls on structural performance of the RC frame. The shear resistant mechanism of the RC frames was clarified from the test and the finite'element analysis (2-D non-linear analysis). The load-displacement relationship of the RC frame can be predicted by this method verified with the shear resistant mer.hanisms