Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
Original Papers
An Electrochemical Biosensor for Nitric Oxide Based on Silver Nanoparticles and Hemoglobin
Xin GANTao LIUXiaoli ZHUGenxi LI
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ジャーナル フリー

2004 年 20 巻 9 号 p. 1271-1275

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抄録
A nitric oxide (NO) biosensor based on silver nanoparticles was fabricated with high sensitivity and selectivity as well as stability. Silver nanoparticles could preserve the microstructures of hemoglobin, but the electrochemical reactivity of the protein and its detection sensitivity toward NO could be greatly enhanced. Accordingly, a NO biosensor was developed. The linear concentration range was from 1.0 × 10-6 to 5.0 × 10-5 M. Its detection limit was 3.0 × 10-7 M with a sensitivity of 0.0424 µA µM-1 NO. The possible co-existing compounds would not interfere with the detection.
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© 2004 by The Japan Society for Analytical Chemistry
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