Terahertz Absorption Spectra of Original and Generic Ceftazidime

Masaya KAWASE; Tadashi SAITO; Masafumi OGAWA; Hideki UEJIMA; Yasutoshi HATSUDA; Sonoyo KAWANISHI; Yoshihiko HIROTANI; Michiaki MYOTOKU; Kenji IKEDA; Keisuke TAKANO; Masanori HANGYO; Kohji YAMAMOTO; Masahiko TANI

doi:10.2116/analsci.25.1483

Notes

Terahertz Absorption Spectra of Original and Generic Ceftazidime

Masaya KAWASE, Tadashi SAITO, Masafumi OGAWA, Hideki UEJIMA, Yasutoshi HATSUDA, Sonoyo KAWANISHI, Yoshihiko HIROTANI, Michiaki MYOTOKU, Kenji IKEDA, Keisuke TAKANO, Masanori HANGYO, Kohji YAMAMOTO, Masahiko TANI

著者情報

ジャーナルフリー

2009 年 25 巻 12 号 p. 1483-1485

DOI https://doi.org/10.2116/analsci.25.1483

詳細

抄録

The absorption spectra of ceftazidime and its generic versions (Modacin, Mosyl, and Mobenzocin) have been measured by terahertz time domain spectroscopy (THz-TDS). Differences in the THz absorption were observed between the original and generic versions. The results show small, but significant differences in the states of ceftazidime hydrate between the original and generic versions. THz-TDS can be used to evaluate the stability of medicines as well as to control their quality.

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