Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
Original Papers
Label-free Detection of Antigen Protein Using a Metal Mesh Device Surface-modified by an Antibody
Hirokazu SETOSeiji KAMBATakashi KONDOYuichi OGAWAYu HOSHINOYoshiko MIURA
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電子付録

2015 年 31 巻 3 号 p. 173-176

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A biosensor for protein detection was developed using antibody-immobilized metal mesh devices. Antihemoglobin antibodies were covalently immobilized on a metal mesh device. Extraordinary transmission with a dipped structure was observed for a metal mesh device immobilized with antihemoglobin antibodies as well as for the original metal mesh device. Hemoglobin in the mixture solution containing albumin at a hundred-fold concentration was detectable using antihemoglobin-immobilized MMDs. The detectability using the antihemoglobin-immobilized metal mesh device was similar to that of a commercially-available kit for the qualitative determination of hemoglobin.
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© 2015 by The Japan Society for Analytical Chemistry
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