BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells

Akira TSUCHIYA; Siti N. HASHIM; Shoko ISE; Takafumi FURUHATA; Kiyohiko KAWAI; Rie WAKABAYASHI; Masahiro GOTO; Noriho KAMIYA; Shinsuke SANDO

doi:10.2116/analsci.32.543

Original Papers

BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells

Akira TSUCHIYA, Siti N. HASHIM, Shoko ISE, Takafumi FURUHATA, Kiyohiko KAWAI, Rie WAKABAYASHI, Masahiro GOTO, Noriho KAMIYA, Shinsuke SANDO

著者情報

キーワード: Aptamer, fluorescent sensor, IFN-γ, ATP

ジャーナルフリー
電子付録

2016 年 32 巻 5 号 p. 543-547

DOI https://doi.org/10.2116/analsci.32.543

詳細

抄録

An on-cell aptamer sensor has the potential to reveal cell–cell communications by signalling molecules. We attempted to design new fluorescent aptamer sensors for the sensing of IFN-γ and adenine compounds on cells. BODIPY-labeled external quencher-free aptamer sensors have allowed a turn-on detection of the target molecule with improved off/on efficiency.

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