Design and Application of Multi-functional Electrogenerated Chemiluminescence Imaging Analyzer

Guangfu JIANG; Xia LIU; Yaqin WANG; Sanpeng RUAN; Honglan QI; Yong YANG; Qishe ZHOU; Chengxiao ZHANG

doi:10.2116/analsci.32.1023

Advancements in Instrumentation

Design and Application of Multi-functional Electrogenerated Chemiluminescence Imaging Analyzer

Guangfu JIANG, Xia LIU, Yaqin WANG, Sanpeng RUAN, Honglan QI, Yong YANG, Qishe ZHOU, Chengxiao ZHANG

Author information

Guangfu JIANG
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University
Xia LIU
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University
Yaqin WANG
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University
Sanpeng RUAN
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University
Honglan QI
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University
Yong YANG
Xi’an Remax Analysis Instruments Co. Ltd.
Qishe ZHOU
Xi’an Remax Analysis Instruments Co. Ltd.
Chengxiao ZHANG
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University

Keywords: Electrogenerated chemiluminescence, imaging analyzer, matrix metalloproteinase 7

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Supplementary material

2016 Volume 32 Issue 9 Pages 1023-1027

DOI https://doi.org/10.2116/analsci.32.1023

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Abstract

A multi-functional eletrogenerated chemiluminescence (ECL) imaging analyzer including both a photomultiplier tube and charged coupled device as detectors has been developed. The ECL imaging analyzer can effectively work for electrochemical study, ECL intensity detection at electrode array, and ECL imaging at bipolar electrodes or electrode array. As an ECL imaging example, an ECL biosensor for visual detection of matrix metalloproteinase 7 in the range from 0.05 to 1 ng/mL is demonstrated.

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