Fluorometric Determination of Epinephrine: A Green Approach

抄録

Herein, a simple, sensitive and selective turn-on fluorescent method for the determination of epinephrine (EP), an important hormone and neurotransmitter, is described. The method is based on the interaction of EP with PEG₆₀₀₀ coated carbon nanoparticles (PCN) resulting in the fluorescence enhancement of PCN. A linear relationship was obtained between the fluorescence intensity and concentration of EP in the 9.90 × 10⁻⁹ – 1.07 × 10⁻⁷ M range; the detection limit being 7.59 × 10⁻¹⁰ M. Furthermore, we demonstrated the application of the present approach in a synthetic urine sample, which suggested its great potential for diagnostic purposes.