Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots

Yusuke OGIHARA; Hiroshi YUKAWA; Daisuke ONOSHIMA; Yoshinobu BABA

doi:10.2116/analsci.33.143

Rapid Communications

Transduction Function of a Magnetic Nanoparticle TMADM for Stem-Cell Imaging with Quantum Dots

Yusuke OGIHARA, Hiroshi YUKAWA, Daisuke ONOSHIMA, Yoshinobu BABA

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Keywords: Bioimaging, stem cell, quantum dots, magnetic nanoparticle, transduction agent

JOURNAL FREE ACCESS

2017 Volume 33 Issue 2 Pages 143-146

DOI https://doi.org/10.2116/analsci.33.143

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Abstract

We investigated the transduction function of a cationic dextran hydroxypropyltrimethyl ammonium chloride-coated magnetic iron oxide nanoparticle (TMADM-03) for transducing quantum dots (QDs) into adipose tissue-derived stem cells (ASCs). As a result, the fluorescence intensity of ASCs labeled with QDs using TMADM-03 was much higher than that of QDs only labeling. These data suggest that TMADM-03 can be useful as a transduction agent for QDs in stem-cell imaging.

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