抄録
The iron(II) catalyzed oxidation reaction of chlorpromazine with hydrogen peroxide in hydrochloric acid solution was studied kinetically by an initial-rate method. All reactions were run at constant ionic strength 0.44mol l-1 and at 30°C and followed by measuring the absorbance at 525nm of the red free radical formed. According to results of a kinetic study of the iron(II) catalyzed reaction, a mechanism is proposed which leads to the following rate equation: R0cat=[Fe(II)]0[CP][H+][H2O2]/(2.0×10-2[CP][H+]+2.2×10-4[H2O2]+1.8×10-3[H2O2][H+]+2.0[CP][H+][H2O2]). The optimal condition for iron determination by initial rate procedure was predicted using this rate equation and analytical implications of the mechanistic study are discussed.
