Highly Sensitive Determination of Aromatic Molecules in Droplets by the Surface Laser Two-Photon Ionization

Abstract

The laser two-photon ionization technique has been applied to a liquid droplet (100-3μl) in order to determine the analytical potential of this technique for a small amount of sample. Surface photoionization was effective to remove the leakage current and allowed use of water as the solvent. Irradiation at the top surface of the liquid drop showed a wider linear range of the analytical curve than irradiation at its middle body. The detection limit of pyrene was 0.3pg.