Abstract
A new moving belt type LC/MS interface (ITF) combining with fast atom bombardment (FAB) ionization has been developed. Unlike the conventional endless belt type ITF, this ITF employs a disposable belt. Furthermore, this incorporates a double belt structure that covers the sample surface with another belt when passing through the differentially pumped region. The performance of LC/MS with this ITF was investigated. This ITF has completely eliminated the problems of memory effect so far encountered. By applying this ITF to the analysis of cyclodextrin mixture, chromatograms and mass spectra based on FAB ionization were obtained.