The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
STUDIES ON TUBERACTINOMYCIN (TUBERACTIN), A NEW ANTIBIOTIC. I
TAXONOMY OF PRODUCING STRAIN, ISOLATION AND CHARACTERIZATION
AKIO NAGATATAKUJI ANDOROKURO IZUMIHIDEO SAKAKIBARATERUO TAKEKAZUO HAYANOJIN-NOSUKE ABE
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1968 Volume 21 Issue 12 Pages 681-687

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Abstract
A new antibiotic, tuberactinomycin, has been isolated from fermentation broth of a streptomyces named Streptomyces griseoverticillatus var. tubei'acticus.Tuberactinomycin is a water-soluble antibiotic belonging to the basic peptide antibiotic group, and markedly stable in acid or neutral solution. Tuberactinomycin is recovered from fermentation broth by means of a cation exchange resin process. Tuberactinomycin shows low toxicity and the activity against pathogenic tubercular bacilli both in vitro and in vivo. Taxonomical study of the producing strain, the isolation and properties of the antibiotic are reported in this paper.
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© Japan Antibiotics Research Association
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