The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
STUDIES ON MITOMYCINS. III
THE SYNTHESIS AND PROPERTIES OF MITOMYCIN DERIVATIVES
MASANAO MATSUI, YASUHIRO YAMADA, KEIZO UZU, TADASHI HIRATA
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1968 Volume 21 Issue 3 Pages 189-198

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Abstract

About sixty derivatives of mitomycin were synthesized from natural mito-mycins and subjected to antibacterial and antitumor tests. Some of them were more effective than mitomycin C. The structure-activity relationship of derivatives were also investigated.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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