ANTIBIOTIC 6640, A NEW MICROMONOSPORA-PRODUCBD AMINOGLYCOSIDE ANTIBIOTIC

MARVIN J. WEINSTEIN; JOSEPH A. MARQUEZ; RAYMOND T. TESTA; GERALD H. WAGMAN; EDWIN M. ODEN; J. ALLAN WAITZ

doi:10.7164/antibiotics.23.551

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

ANTIBIOTIC 6640, A NEW MICROMONOSPORA-PRODUCBD AMINOGLYCOSIDE ANTIBIOTIC

MARVIN J. WEINSTEIN, JOSEPH A. MARQUEZ, RAYMOND T. TESTA, GERALD H. WAGMAN, EDWIN M. ODEN, J. ALLAN WAITZ

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1970 Volume 23 Issue 11 Pages 551-554

DOI https://doi.org/10.7164/antibiotics.23.551

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Abstract

Antibiotic 6640 is a new aminoglycoside antibiotic isolated from fermentation broths of a new species of the genus Micromonospora, named Micromonospora inyoensis. It has been differentiated from other known related antibiotics by a variety of chemical and biological methods. Its spectrum of activity appears to be quite similar to that of gentamicin in vitro and in vivo. The acute toxicity is approximately twice that of gentamicin in mice.

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