DIKETOCORIOLIN B, AN ACTIVE DERIVATIVE OF CORIOLIN B PRODUCED BY CORIOLUS CONSORS
1971 年 24 巻 9 号 p. 631-635
詳細
1971 年 24 巻 9 号 p. 631-635
Coriolus consors was cultured under aeration, and from the mycelial cake coriolin B, a sesquiterpene compound, was extracted and purified. Coriolin B showed no antimicrobial activity. However diketocoriolin B which was obtained by the oxidation of coriolin B showed antibacterial and antitumor activities. Diketocoriolin B prolonged the survival period of mice inoculated intraperitoneally with mouse leukemia L-1210 cells or Ehrlich carcinoma cells.
