The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
BIOSYNTHESIS OF LASALOCID. II
X-RAY ANALYSIS OF A NATURALLY OCCURRING ISOMER OF LASALOCID A
J.W. WESTLEYJ.F. BLOUNTR.H. EVANS, Jr.A. STEMPELJ. BERGER
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1974 年 27 巻 8 号 p. 597-603

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抄録
A search for precursors of lasalocid A has led to the isolation and X-ray crystallographic analysis of an isomer of the antibiotic. The isomer differs from lasalocid A in both the size and absolute configuration of the terminal cyclic ether. These differences lead to speculation on the nature of cyclization mechanisms involved in the biosynthesis of lasalocid A and the other polyether antibiotics.
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© Japan Antibiotics Research Association
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