The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
NORVALINE ACCUMULATION BY REGULATORY MUTANTS OF SERRATIA MARCESCENS
MASAHIKO KISUMIMASAKI SUGIURATSUTOMU TAKAGIICHIRO CHIBATA
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1977 年 30 巻 1 号 p. 111-117

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抄録
A gene coding for desensitized L-threonine dehydratase was transduced with phage PS20 into a leucine accumulator of Serratia marcescens Sr41. The transductant converted L-threonine to α-ketobutyrate, a precursor of both norvaline and isoleucine. An isoleucine-valine auxotroph of the transductant accumulated large amount of norvaline from L-threonine as well as from D-threonine.
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© Japan Antibiotics Research Association
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