STUDIES ON NEW ANTIFUNGAL ANTIBIOTICS, GUANIDYLFUNGINS A AND B

I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

Abstract

Guanidylfungin A, C₅₈H₁₀₃N₃O₁₈, and guanidylfungin B, C₅₇H₁₀₁N₃O₁₈, were isolated from the mycelia of Streptomyces hygroscopicus No. 662 by means of silica gel absorption and reversed phase liquid chromatographies. The guanidylfungins were active against fungi and Gram-negative bacteria.