APHE-1 AND APHE-2, TWO NEW ANTIMICROBIAL AND CYTOTOXIC ANTIBIOTICS
II. PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE ELUCIDATION
1992 年 45 巻 11 号 p. 1759-1762
詳細
1992 年 45 巻 11 号 p. 1759-1762
Two new pyrazolo-isoquinolinone antibiotics, APHE-1 and APHE-2, have been isolated from the culture nitrate and mycelia of Streptoverticillium griseocarneum NCIMB 40447. Molecular formulae were established as C13H12N2O for APHE-1 and C14H14N2O for APHE-2, by elemental analysis, NMR and mass spectra. 2D NMR techniques (1H-1H COSY-45 and 1H-13C correlated spectroscopy) have been applied to establish their structures.
