APHE-1 AND APHE-2, TWO NEW ANTIMICROBIAL AND CYTOTOXIC ANTIBIOTICS I. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITY

M. L. FIDALGO; J. L. ALONSO; J. SOLIVERI; M. E. ARIAS

doi:10.7164/antibiotics.45.1753

APHE-1 AND APHE-2, TWO NEW ANTIMICROBIAL AND CYTOTOXIC ANTIBIOTICS

I. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITY

M. L. FIDALGO, J. L. ALONSO, J. SOLIVERI, M. E. ARIAS

著者情報

ジャーナルフリー

1992 年 45 巻 11 号 p. 1753-1758

DOI https://doi.org/10.7164/antibiotics.45.1753

詳細

抄録

APHE-1 and APHE-2 are two new antibiotics produced by Streptoverticillium griseocarneum NCIMB 40447. They exhibited a remarkable cytotoxic activity against several tumor cell lines from different origin. Furthermore, they showed weak antimicrobial activity against Gram-positive bacteria, filamentous fungi and yeasts.

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